Centrum Diagnostyki Laboratoryjnej - VANADIS prenatal tests
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Non-invasive prenatal test VANADIS NIPT

VANADIS is a non-invasive, screening, prenatal test. Since the 10th week of pregnancy you can receive vital information about the health of your child. Vanadis allows you to calculate the risk of appearance of an additional chromosome, which would mean serious development defects. Most commonly occurring defects are: Down's syndrome (trisomy of chromosome 21), Edward's syndrome (trisomy of chromosome 18) and Patau's syndrome (trisomy of chromosome 13). Vanadis also allows you to determine child's sex. .

To perform the test the only thing needed is a small blood sample of the mother. Blood's plasma will contain child's DNA which will be analysed (cffDNA). Vanadis' sensitivity in case of 21 and 13 trisomies is 100%. Because of that manu future mothers can avoid more invasive tests (like amniocentesis). Tests results are available within 10 working days since the delivery of the sample.

Test's purpose: The purpose of non-invasive prenatal test VANADIS is screening the fetus in order to find chromosomal aberrations. In addition to the screening test it is also possible to determine the sex of the child. Vanadis is available for women after their 10th week of pregnancy, in order to make sure of sufficient level of cffDNA in the bloodstream. The deliverer of medical services can provide further information on chromosomal aberration which presence this test verifies.

What makes Vanadis unique?

Breakthrough Technology
eliminating PCR and sequencing in order to enable cffDNA testing in any laboratory.

Service and support by PerkinElmer
world leader in the field of prenatal testing.

State-of-the-art screening software
to calculate risk, supporting involvement of all models of screening tests.

Full automation
enabling of improved workflow to increase productivity.

High-precision technology
improvement of possibility of detection and minimisation of no connection indicator with simultaneous introduction of NIPT screening tests to wider populace.

No need to send samples outside Polish borders
Blood samples do not have to be sent to far away places (like the USA in the case of other prenatal tests based off mother's blood sample).

Chromosomal aberrations analysed by VANADIS:

Trisomy of chromosome 21

Birth defect known as Down's syndrome is caused by an additional copy of chromosome 21. It is the most common cause of mental handical. It appears within 1 in 830 babies born alive. People affected by Down's syndrome commonly possess IQ level of around 50 and always are to some extent mentally handicapped. Some children affected by this syndrome are also affected by organ defects which may require surgeries or treatments. Other issues such as hearing and sight defects might also appear.

Trisomy of chromosome 18

Birth defect known as Edward's syndrome is caused by an additional copy of chromosme 18.This trisomy affects 1 in 7500 of live born children and causes a serious mental deficiency Most children with Edward's syndrome are also affected by defects of heart and other organs. The syndrome often weakens growth during pregnancy often causing miscarriage or delivery of a dead baby. Children born successfully often do not live through the first year of their lives – if they do they are laden with deep mental and developmental problems.

Trisomy of chromosome 13

Birth defect known as Patau's syndrome is caused by an additional copy of chromosome 13. This trisomy affects 1 in 22 720 live born children and causes a serious mental handicap. Most children affected by this trisomy are also affected by heart and organ defects. Many pregnancies end with a miscarriage or delivery of a dead baby. Many babies do not live through the first year of their life.